WebbStoesser, N., Mathers, A. J., Moore, C. E., Day, N. P., & Crook, D. W. (2016). Colistin resistance gene mcr-1 and pHNSHP45 plasmid in human isolates of Escherichia ...
Fitness Advantage of mcr-1–Bearing IncI2 and IncX4 Plasmids in Vitro
Webb28 nov. 2016 · Abstract. Polymyxins are the last line of defense against lethal infections caused by multidrug resistant Gram-negative pathogens. Very recently, the use of polymyxins has been greatly challenged by the emergence of the plasmid-borne mobile colistin resistance gene ( mcr-1 ). However, the mechanistic aspects of the MCR-1 … Webb7 mars 2016 · A transferable plasmid conferring resistance to colistin was discovered in Escherichia coli and Klebsiella pneumoniae from China and was confirmed to have carbapenemase-producing properties. Colistin is considered a last resort for the treatment of infections caused by carbapenemase-producing members of the family … philhealth other term
Comprehensive resistome analysis reveals the prevalence of NDM …
WebbOne mcr-1-carrying Salmonella enterica serovar Indiana strain D90, was identified from 1320 Salmonella enterica isolates from poultry slaughterhouse in 2012 in China. The objective of this study was to verify the transferability of the mcr-1 gene and also completely characterize the sequence of the strain at the whole-genome level. Broth … Webb27 feb. 2024 · Fitness Effects of mcr-1 Gene and mcr-1 Plasmids in Vitro. The impact of plasmids pHNSHP45, pHNSHP45-2, pHNSHP23, pHNSHP17 and pHNSHP24 on host fitness was evaluated by direct competition assays of plasmid-carrying E. coli DH5α against plasmid-free E. coli DH5α. The transformants with pHNSHP45(IncI2) or … WebbThe Lancet Infectious Diseases 2016 16, 283-284DOI: (10.1016/S1473-3099(16)00012-8) 21 Blast comparison with pHNSHP45 showed 100% similarity only in a short, 2604 bp … philhealth outlets